Low-Dose Naltrexone: A Promising Off-Label Option for Fibromyalgia Relief

A New Option for Chronic Pain Relief

A decades-old medication once used to treat addiction is emerging as a breakthrough in managing fibromyalgia—a chronic condition marked by pain, fatigue, and brain fog. Low-dose naltrexone (LDN), typically compounded in doses of 1–6 mg, has been reported to help up to 70% of patients experience meaningful symptom relief, according to new clinical reports and physician experience.

Originally approved at much higher doses for opioid and alcohol use disorders, naltrexone works differently at lower doses—helping reduce inflammation in the nervous system and regulate pain signals rather than blocking opioids.

How Low-Dose Naltrexone Works

Research suggests that fibromyalgia pain may be linked to overactive glial cells—immune-like cells in the nervous system that cause inflammation and heighten pain perception. LDN appears to calm this inflammatory response, easing widespread pain, fatigue, and mood symptoms.

Patients who respond to LDN often report:

• Significant reduction in pain intensity

• Improved energy and cognitive clarity

• Better sleep and emotional well-being

In clinical studies, nearly two-thirds of fibromyalgia patients experienced measurable improvements in pain and fatigue.

Why LDN Is Worth Considering

Unlike many traditional fibromyalgia medications that can cause sedation, weight gain, or dependence, LDN is low-cost, non-addictive, and generally well-tolerated. Side effects—like vivid dreams or mild headaches—are usually temporary.

While large-scale trials are still needed, early evidence and real-world success stories show that LDN may be a game changer for patients who haven’t found relief elsewhere.

At Oasis Wellness & Recovery, we believe in exploring safe, evidence-informed options like LDN that help patients take back control of their health.

Restoring Hope at Oasis Wellness & Recovery

If you’re living with chronic pain, fatigue, or fibromyalgia, you don’t have to keep struggling. Dr. Eric Milbrandt and the Oasis team offer personalized care rooted in compassion and science, including off-label treatments like LDN and IV ketamine therapy for pain and mood disorders.

🔍 Learn more about LDN

🌿 Schedule your consultation today to learn whether low-dose naltrexone could be right for you.

📍 Oasis Wellness & Recovery — Ocala, FL

www.oasiswr.com | (352) 325-5755