Ketamine for Chronic Pain: A Promising Option When Nothing Else Has Helped

Relief for CRPS, Neuropathy, Cancer-Related Pain, Headache Disorders, and More

Chronic pain is one of the most frustrating and life-altering conditions we treat. For many people, the pain becomes a daily companion—limiting activity, disrupting sleep, and draining emotional and physical energy. Standard treatments don’t always work, and even when they do, they often provide only partial or temporary relief.

This is where IV ketamine therapy can offer new hope.

At Oasis Wellness & Recovery, we provide medically guided ketamine therapy for chronic pain conditions, including:

• Complex Regional Pain Syndrome (CRPS)

• Peripheral neuropathy

• Cancer-related pain

• Headache and migraine disorders

• Musculoskeletal pain

• Persistent pain that has not responded to standard treatments

How Ketamine Helps Chronic Pain

Ketamine works differently from traditional pain medications. Instead of masking pain signals, it acts on NMDA receptors and the glutamate system, helping interrupt the cycles of pain sensitization that keep the nervous system “stuck.”

This mechanism allows ketamine to:

• Reduce central sensitization

• Calm overactive nerve pathways

• Improve functional mobility

• Reduce pain intensity and pain-related emotional distress

• Support neuroplasticity, allowing the nervous system to “reset”

The result can be profound—especially for people who feel like they’ve reached the end of the road with other treatments.

What the Research Shows

A recent Cleveland Clinic study showed that 20–46% of patients experience clinically meaningful improvement in chronic pain with IV ketamine therapy. While it doesn’t help everyone, it is often most effective for people who have struggled for years without significant relief.

And when ketamine does work?

Patients tell us things like:

“I can’t remember feeling this good before.” “It’s like someone flipped a switch and quieted the pain.” “I finally feel like myself again.”

For our team, these transformations make this work incredibly rewarding. Helping people regain movement, confidence, hope, and quality of life is the heart of what we do.

What to Expect from Treatment

A typical chronic pain series involves:

• A personalized consultation with our clinical director

• A series of IV infusions spaced over several days

• Ongoing assessment to measure progress and durability

  
  

Some patients experience relief after the first few treatments, while others notice improvement more gradually over the course of the series.

Is Ketamine Right for You?

Ketamine may be a promising option if you:

• Have chronic pain that has not responded to standard treatments

• Want a non-opioid alternative with strong research support

• Are living with CRPS, neuropathic pain, migraines, or cancer-related pain

• Want a therapy that may improve both physical and emotional well-being

Our goal is always the same: to help you reclaim comfort, function, and joy in your daily life.

Ready to Explore IV Ketamine Therapy for Pain Relief?

We’re here to help—and we can often schedule new clients within a few days.

📞 Call us today: 352-325-5755

🌿 Oasis Wellness & Recovery – Ocala, Florida